Oprah Winfrey Declares Taking Weight-Loss Drugs Like Ozempic and Wegovy Woke Her Up to Truth About 'Thin People' — After Denying She Used Meds to Shed Flab

Winfrey, now close to her goal weight of 160 pounds, opened up on her podcast about using the medication and the insights it has given her on "thin people" while discussing the drug's function and safety with Dr. Ania Jastreboff.

She confessed: "'One of the things that I realized the very first time I took a GLP-1 was that all these years I thought that thin people had more willpower.

"They ate better foods. They were able to stick to it longer. They never had a potato chip."

After starting a GLP-1 medication, Winfrey realized what she had considered "willpower" was actually the lack of constant hunger, or "food noise."

These medications, such as Ozempic and Wegovy, reduce cravings and slow digestion, helping to curb overeating and prevent weight gain.

She continued: "And then I realized the very first time I took the GLP-1 that, they're not even thinking about it.

"They're eating when they're hungry and they're stopping when they're full."

Winfrey noted the traditional approach to eating "doesn't work" for those struggling with obesity, which she called a "disease."

"And I accepted it because I thought I deserved it."

However, she no longer believes she deserved such treatment.

After previously denying the use of weight-loss drugs, Winfrey declared in December 2023 she was "done with the shaming" and openly admitted to using a GLP-1.

The talk show host also added regular exercise to her routine to help shed the extra weight.

She told People: "I now use it as I feel I need it, as a tool to manage not yo-yoing.

"The fact that there's a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for.

"I'm absolutely done with the shaming from other people and particularly myself."

Winfrey revealed she started taking the medication before Thanksgiving, knowing she'd have "two solid weeks of eating," and credited it for gaining only half a pound instead of eight.