Johnny, 48, attended the Golden Globes on Sunday sans Vanessa, 39, and People magazine claims the couple hasn't walked a red carpet together in more than a year.
"He had his head down and he did not smile. He looked messy," an eyewitness told the magazine. "He walked off stage and went right out the back door."
As RadarOnline.com was first to tell you, his personal life is falling apart as his relationship with Vanessa crumbles.
"Johnny isn't handling anything well right now," a source close to the Pirates of the Caribbean star told us. "People around him are worried about how Johnny is doing because he and Vanessa seem so fractured right now. Their relationship is heading toward the end."
So much so, that the couple is secretly ending their very public relationship — and they've even contacted attorneys.
"Johnny has started reaching out to lawyers, probably to quietly discuss how to get out of the relationship. They're not married but they've been together for years and have kids together so it isn't as easy as just breaking up," the source said. "Johhny is so talented at acting, but he doesn’t seem able to hide how badly things are going right now."