The Your Body Is A Wonderland singer tells the new edition of Rolling Stone that Swift's country ballad Dear John made him feel "terrible," as he looked at it as a series of cheap digs communicated through shoddy songwriting, via his rumored love interest that year.
Some of the 2010 song's possible-powderkeg lyrics include the lines: "Dear John, I see it all, now it was wrong … don't you think 19 is too young to be played by your dark twisted games, when I loved you so?"
The 34-year-old Daughters singer told the magazine: "I was really caught off-guard, and it really humiliated me at a time when I'd already been dressed down. I mean, how would you feel if, at the lowest you've ever been, someone kicked you even lower?"
Mayer, known for his past flings with Jennifer Aniston and Jessica Simpson, said the song also really rubbed him the wrong way because he didn't deserve the flak.
"I'm pretty good at taking accountability now, and I never did anything to deserve that," he said. "It was a really lousy thing for her to do.
"I know she's the biggest thing in the world, and I'm not trying to sink anybody's ship, but I think it's abusing your talent to rub your hands together and go, 'Wait till he gets a load of this!' -- that's bullsh*t," said Mayer, adding he "never got an e-mail … or a phone call" about the song in advance.
Mayer said he didn't "want to go into" discussing a lyric in the song that asked, "Don't you think I was too young to be messed with?"
Mayer's new album, Born and Raised, is in stores now. The new issue of Rolling Stone hits newsstands Friday.