Leaping Lizards! Johnny Depp's 'Rango' Rules The Box Office


Mar. 6 2011, Updated 10:45 a.m. ET

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It didn't open to the kind of numbers that had been hoped for but the animated Rango took first place at the weekend box office, bringing in an estimated $38 million in tickets.

Depp is the voice of a chameleon named Rango. Isla Fisher, Abigail Breslin and Depp's good buddy Harry Dean Stanton also lent their voices to the flick.

VIDEO:  Johnny Depp Lets His Inner Kid Out While Voicing Rango

Matt Damon's The Adjustment Bureau opened in second place.  Its $21 million in ticket sales was actually slightly higher than had been predicted.

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