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SNEAK PEEK: Courteney Cox and David Arquette's Final Movie As A Married Couple -- It's A Scream (4)

Oct. 21 2010, Published 12:09 p.m. ET

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It might be the last time you will see Courteney Cox and David Arquette together in a movie and it’s guaranteed to draw some blood! RadarOnline.com has your first peek at the steamy trailer for Scream 4.

SNEAK PEEK: Courteney Cox & David Arquette In The Scream 4 Trailer

The newly separated couple filmed the horror flick together in Michigan over the summer before announcing their separation on October 11.

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Just days after announcing their split, Arquette gave a shockingly candid interview to Howard Stern in which he admitted to sleeping with mistress Jasmine Waltz.

Fourteen years have passed since Cox and Arquette met on the set of the original Scream movie – with their 11-year marriage permanently ending after finishing up the fourth movie in the Wes Craven series.

The movie picks up with lead character Sidney Prescott – played by Neve Campell – ten years later as she attempts to put her life back together, only to be revisited by the Ghostface Killer.

Arquette plays Sheriff Dewey Riley and Cox reprises her role as the feisty investigative reporter, Gale Weathers-Riley.

The movie is scheduled to hit theatres in April 2011.

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