Following Giuliana Rancic's bold admission she's "really thin" due to cancer medication, RadarOnline.com takes a look at the E! star's changing body over the past 12 years.
Rancic, then known under her maiden name of Giuliana DePandi, looked stunning in this October 2003 shot from a Richard Tyler fashion show in Los Angeles.
Rancic sported a bohemian style on the red carpet of a Cosmo event in August of 2005, the year she became an anchor for E! News.
Three months after that, she looked ravishing in a red satin dress while attending the Vibe Awards.
The E! beauty, looking flawless at the 2006 Emmys, made plenty of headlines this week addressing the ongoing controversy surrounding her figure.
Rancic begins to show a bit of a gaunt look in this shot from the 2007 Grammys. Later that year, she'd tie the knot with her husband Bill, winner of the initial edition of The Apprentice.
The Fashion Police star shows a bit of cleavage, looking fit at a September 2008 event.
Rancic appeared a bit scrawny at this May 2009 event, though her hair and skirt covered any possible scary skinny signs.
Rancic is clearly thin at this August 2010 marathon, which preceded her 2011 cancer battle she blames her bony frame on.
Rancic was well covered in this fashionable ensemble in April 2011, but showed a thinned-out, gaunt face.
Rancic sports a very thin frame at this 2013 E! showcase. She said that in recent years, she's struggled with her image, admitting, "I want to look fit and beautiful and sexy, and I can't ... I look in the mirror and it's hard for me."
Rancic, seen here at the 2014 Grammys, blamed a battle with scoliosis throughout her teens for her bony shoulders in her tell-all, Going Off Script.
The 40-year-old's current look, in this 2015 shot, seems especially gaunt. She told People, "I'm sorry that some people think I'm disgustingly skinny, as they put it, but there's nothing I can do -- I'm lucky that I even have the type of cancer that reacts to the medicine."