"She seemed to go pale and got very quiet putting pressure on it and whispering to Ina that it was bad," an eyewitness tells RadarOnline.com exclusively. "She looked like she was about to faint."
The show broke for commercial and when it returned, Brown announced De Laurentiis had left the set to get medical attention.
The episode brought back memories of one of Saturday Night Live's most iconic sketches featuring Dan Aykroyd as the legendary Julia Child who once cut her hand and bled while taping an episode of her classic cooking show, The French Chef.
But the show must go on, and De Laurentiis came back about 15 minutes later with her finger bandaged.
She explained it had bled quite a bit but with a cold compress and lots of pressure, the on-set medic had gotten it to stop.
In the Food Network's follow-up website program, Hangout After the Show, De Laurentiis even gamely took on plenty of good-natured ribbing of her fellow chefs.