Stay Home Los Angeles -- Carmageddon Is Coming!

America’s Got Talent judge Piers Morgan thinks the city is over-reacting saying, “Re this whole #Carmageddon nonsense in LA this weekend - try coming to London, it's #Carpocalypse there every day.”

A 10-mile section of the 405 will be closed from 7 p.m. on Friday until 6 a.m. on Monday, leading many businesses to close early and many companies to let their employees out of work early on Friday (Hint! Hint!) to avoid the dreaded gridlock.

The 405 is the nation’s most congested highway – on a typical weekend, 500,000 cars pack it.

Check out what other celebs are saying about Carmageddon:

Zooey Deschanel: “Getting ready for 'carmageddon' just excited it's not karma-karma-karma-karma-karma-mageddon! because that one comes and goes. #boygeorge.”

Soleil Moon Frye: “LAPD contacted me about #Carmageddon this weekend Perfect chance 2 be green,ride bikes & actually walk in LA.Stay off the freeway 16 & 17th.”

David Spade: “nostradamus predicted carmageddon... and i think mob wives.. and possibly hoarders but i may be wrong.”

Kevin Smith: “LOS ANGELES! The LAPD asks that I remind you the end is nigh, as #CARMAGEDDON approacheth! July 16-17, the 405 Fwy CLOSED btwn the 10 & 101!”

Fred Willard: “#carmageddon is coming so I am going to New York. Take that, 405.”

Mindy Kaling: “I bet you there'll be so many babies conceived during Carmageddon.”

Antonio Villaraigosa: “It doesn’t have to be #Carmageddon! The @I_405 closure is a chance to stay local & enjoy neighborhood activities. Send ideas to #405things.”

Twitter is also a-buzz with airline JetBlue offering $4 flights between Long Beach and Burbank, in an effort to avoid the mayhem and boost their business.

Jay Leno jokes about the impending carpocalypse on The Tonight Show. Watch the clip below: