VIDEO: Kate Gosselin Kisses George Lopez, Then It's Open Season On Jon

Kate Gosselin and George Lopez had great chemistry in the reality mom's appearance on Lopez Tonight Monday, making for a five-star laughfest in which Lopez proved he's one of the funniest men in late night.

Lopez, at the beginning of the segment, invited the mother-of-eight to slap him in the face for all of the jokes he's aimed at her in his monologues, but she gave him a peck on the cheek instead.

Of the late night host's "Keep Kate Alive" campaign he drummed up during her comical stint on Dancing With The Stars, Kate said: "You know, thank you, because at the time I was like, 'Is he doing it sarcastically or for real?'"

Despite a few embarrassing moments and the agony of defeat, Kate said she ultimately benefited from appearing on the ABC dance hit.

"I learned a lot about myself," she said, noting that her stint on the show sparked a passion within her for running. She said she can now run eight miles on a good day, and is hoping to run a marathon in the near future.

"It feels very symbolic of my life," Gosselin said. "No looking back, you gotta just keep going."

Then came the topic of Kate's love life, and her ex Jon was directly in the host's comedy crosshairs.

Asked about what's new there, Kate said, "I've been on a few little dates here and there but I have eight kids already... I don't need nine."

"But Jon, your ex, was like a child, he was very childish," Lopez joked.

"You said it!" Kate replied.

Watch the video on RadarOnline.com

"When you see somebody in an Ed Hardy shirt, do you throw up in your mouth a little bit?" Lopez asked.

"Next question... that was all after me," she said of Jon's summer 2009 shenanigans, in which he was photographed sporting clothes from the line on a daily basis.

"He might have killed that company," Lopez said. "You've moved past that: you want a man in a t-shirt that doesn't have a dragon on it."