Charlie Sheen's Ex Brooke Mueller Checks Into Rehab

Brooke Mueller has checked back into rehab, multiple reports confirm.

Charlie Sheen's ex, who has struggled with substance abuse for many years, is set to participate in a treatment program for six months, and has already spent a month and a half at a facility, sources confirm.

The revelations of her rehab care come just two months after ex-husband Charlie — with whom she shares six-year-old twins Bob and Max — admitted to being HIV positive.

"Brooke has been inundated with calls from friends and family," Mueller's rep, Steve Honig, told Us Weekly in a statement. "To put their minds at ease, Brooke can confirm that she and the boys are not HIV-positive."

The former couple has a very complicated past. In 2010, Sheen expertly avoided jail time, attending a Malibu rehab facility after allegedly holding a knife to then-wife Mueller's neck on Christmas vacation in Aspen, Colo.

Meanwhile, Mueller has had a number of rehab visits herself, including 90 days in 2012 after an arrest for drug and assault charges, and once before that, in 2010.

In an exclusive interview with RadarOnline.com, Sheen claimed that Mueller has been supportive of his HIV diagnosis, saying, "She was sad for me but then realized that I'm a pretty tough customer and she knew I would handle it and do whatever I had to."