Christina Applegate Admits She Was 'Humiliated' at Walk of Fame Ceremony as Actress Didn't Look Like Herself Following MS Diagnosis

Christina Applegate says she 'no longer had control' of her life after her MS diagnosis.
March 3 2026, Updated 1:15 p.m. ET
Christina Applegate felt "humiliated" on the day she got her star on the Hollywood Walk of Fame in 2022, RadarOnline.com can reveal.
In her new book, You With the Sad Eyes: A Memoir, Applegate notes it was the first time anyone had seen her since she had been diagnosed with MS and she didn't feel like she looked like herself.
Christina Applegate 'Hated' How She Looked the Day She Got Her Star

Christina Applegate notes she was 'embarrassed' by how she looked at the Hollywood Walk of Fame ceremony.
She adds she thought she'd have to "go off the rack for the ceremony," something "no one" in Hollywood does, until "Christian Siriano came to my rescue and made me something beautiful to wear."
"I hated how I looked that day, how much this illness had taken from me, but this was my Oscar, after all. It was time to step out in public," she writes.
"For a year or more, people saw only this weird version of me created by those steroid infusions. For all the joy of finally getting my star, it was still humiliating and horrible and devastating to be seen this way," she continues. "Not just because I was bigger – that was one thing – but because the girl who had control all her life no longer had that control."
Christina Applegate Felt 'Everyone' Was 'Staring' at Her

Christina Applegate states walking with a cane was her 'new normal.'
Applegate claims she wants to "throw up" when she thinks about the pictures of her that are out there as she feels she looks "sad" and "embarrassed."
She also says she felt like "everyone" was "staring" at her.
"Once people stared at my boobs. But now I knew they were staring not only because I was disabled; they were staring because I was fat, forever an unacceptable fate for women in Hollywood. 'Oh wow,' I could imagine everyone saying. 'Christina Applegate, of all people, is fat. Not to mention she’s got a cane. Not to mention she’s got a disease,'" she shares.
"When I walked out on stage to do Jimmy Kimmel’s show three years after my diagnosis, I was touched when he said, 'For people, it’s a little bit shocking. You come out with a cane and people love you and are concerned about you,'" she adds. "As I told him, this was my now, my normal."
Christina Applegate Talks Weight Loss

Christina Applegate didn't 'look in the mirror for a year' due to her weight loss.
As Radar previously reported, Applegate's shocking weight loss bothered her so much she didn't "look in the mirror for a year."
She also claims the weight sometimes "bothered" her more than "the disease," as a clear-liquid diet she was put on caused "everything" to drop off of her.
"Within seven months, all of it was gone, and I was down by 50 pounds or more. These days, my legs are tinier than they’ve ever been," she says.
MS Caused Stomach Issues for Christina Applegate


Christina Applegate claims she's ended up in the emergency room 'so many times recently.'
Applegate first received her diagnosis of MS in 2021. In her memoir, she reveals MS was responsible for "serious" stomach issues that caused her to drop so much weight.
"As I write this, there are tamales downstairs that are the best tamales you could ever have," she pens. "I want to eat five of them right now, I’m so hungry – but I know if I do, I’ll probably end up in the ER again, as I have so many times recently."



