The talk show host is asking $8,750,000 for the property that' in L.A.'s celeb-packed Brentwood neighborhood, according to the real estate website, Redfin.
The plantation-style main house have five bedrooms and four baths. There's a separate one-bedroom guest house.
The one-acre property has plush landscaping, with an outdoor kitchen perfect for entertaining.
Lake's attempt to return to the talk show format ended after just one season when her The Ricki Lake Show was canceled earlier this year.
Ironically Lake and Arquette competed against each other on Dancing with the Stars in 2011.