Sep. 12 2010, Published 12:36 p.m. ET

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It’s the biggest party of the year—the 27th annual MTV Video Music Awards are on and it’s set to be a wild night. Comedian Chelsea Handler hosts with performances by Justin Bieber, Kanye West (despite his controversial appearance last year), Florence and the Machine, Drake and B.o.B. Scheduled presenters include Ashley Greene, Justin Timberlake, Ke$ha and more! Plus, Lady Gaga leads the way with a record breaking 13 nominations!

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The other major event tonight is the gripping season finale of True Blood. So much is going down in Bon Temps—will Eric die with Russell? And Sookie gives serious thought to living her life without vampires while Lafayette and Jesus develop a stronger bond and Jason considers changing careers—again!


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