Uma Thurman is one deadly diva, having played deadly assassin The Bride in Quentin Tarantino’s “Kill Bill”.

In “Kill Bill,” Thurman faced and destroyed 88 henchman under the command of Lucy Liu.

Don’t let the dainty blonde fool you, she’s one bad Big Screen killer!

Angelic Charlize Theron looks as though she wouldn’t hurt a fly, but played a badass futuristic assassin in “Aeon Flux”.

Theron donned a skintight black bodysuit to inhabit the character, originating as an MTV cartoon.

Charlize also played serial killer Aileen Wuornos in her Oscar-landing role of “Monster”.

Theron’s real life lady killer is fellow actor Stuart Townsend.

Charlize has the looks of a goddess, but the on-screen wraith of one as well.

Courteney Cox made homicidal heads roll in three installments of the “Scream” franchise.

As Gale Weathers, the self-centered journalist, Cox got her fair share of action taking down the ghost faced killer(s).

These days, Cox spends her time rocking a killer bod on ABC’s “Cougartown”.

Husband David Arquette was her partner in crime on all “Scream” flicks.

Next year, the married actors will reunite to film “Scream 4″ with Neve Campbell and director Wes Craven.

Pamela Anderson may be every boy’s beach dream, but in 1996′s “Barb Wire” the blonde played a deadly assassin.

Barb Wire’s iconic movie poster features Pam bursting out of a vinyl mini with an actual barbed wire tattoo.

Pamela rose to fame playing a good guy, a bountiful lifeguard on “Baywatch”.

Still buxom over 40, Pam keeps busy with stage performing and ad campaigns.

Though her stock and trade is a ditzy blonde, Pam can be the most cunning killer when required.

Eva Mendes is spicy and sweet, but played the deadly Sand Saref in the stylish adaptation of the comic book “The Spirit”.

Mendes wielded her guns and her amazing body as weapons in the film.

Usually a rom-com type of gal, murder was certainly a departure for Mendes.

Mendes will next play the mistress of Greek billionaire Aristotle Onassis.

Eva may be a doe-eyed temptress, but can more than hold her own with a deadly weapon.

Kristen Bell is one slamming’ sociopath, or at least she plays a sadistic
murderous one on NBC’s “Heroes”!

Bell plays another TV bad girl, albeit one that doesn’t thirst for human
suffering (or does she?), as the voice of The CW’s “Gossip Girl”.

Kristen has been linked to the comedian Dax Shepard.

Bell starred in Judd Apatow’s cult comedy “Forgetting Sarah Marshall”.

While Kristen’s character Elle Bishop has a minor story line this season,
don’t take this dangerous beauty for granted.

Angelina Jolie is the definitive killer beauty with a killer body.

Jolie played a dead sexy assassin married to Brad Pitt in “Mr. & Mrs. Smith”.

Jolie is no stranger to war play–guns, knives, hands and those smoky
eyes–from her days playing Lara Croft.

Angelina will play an assassin spy once more in the forthcoming “Salt”.

Sony Pictures has reportedly offered huge bucks for Jolie and Pitt to star
in a Smith sequel.

Rebecca Romijn went from supermodel to super villain, playing the mutant
assassin Mystique in “X-Men”.

As the scaley, sexy killer in blue, Romijn took down important allys of
mutant kind.

Romijn has won Blockbuster and Saturn awards for her portrayal of Mystique.

Lately, Romijn has been romping with Lindsay Price on the bewitching ABC
drama “Eastwick”.

Rebecca is married to actor Jerry O’Connell, with whom she has twin babies.

Megan Fox played likely the sexiest, most lethal high school student ever in
“Jennifer’s Body”.

In Diablo Cody’s script, Fox is a demon who feeds on the flesh of high
school boys.

In her starmaking role, Megan is the damsel in distress Mikaela from the
“Transformers” series.

As Jennifer, not even Shia LaBeouf would stand a chance against her
murderous ways.

Fox will next been seen on billboards worldwide as the spokeswoman for
Armani underwear.

Devon Aoki is an underground pinup girl for her kick-ass assassin character
Miho in the comic book adaptation of Sin City.

Devon was a runway model turned American print star, who recently
transitioned to acting.

Devon’s brother is popular DJ Steve Aoki.

As Miho, Aoki played mute but talked plenty with her deadly hands.

Devon is set to reprise her lethal role in “Sin City 2″, due out in 2010.