AUDIO: Howard Stern Grills David Arquette On Life After Courteney Cox

Who needs a therapist when you've got Howard Stern's ear?

Just a night after he attended the Scream 4 premiere in Hollywood, a straight-off-the-Red-Eye David Arquette appeared in Stern's New York City studios Tuesday, where he told the radio icon about his recent interactions with his estranged wife Courteney Cox, who he separated with last fall.

Stern immediately went for the jugular, asking the quirky actor about recent pictures of Cox on vacation in St. Barth’s with their daughter Coco and her Cougar Town co-star Josh Hopkins.

"You swear she's not f**king these guys?" Stern asked Arquette, who answered, "I swear, she's not!"

"Then why is she on vacation with her and your daughter and all that stuff?" Stern countered.

"We're married, but we’re not together, so she can do whatever she wants," Arquette answered, adding he was "a little upset" he didn't go to St. Barth's.

Stern continued prodding Arquette about Cox's post-separation love life, spurring Arquette to tell him, "She hasn't f**ked anyone!"

Stern also prodded Arquette about his recent trip to Disney World with Cox their daughter, Coco.

"How far did you get with her? A kiss?" Stern asked.

"A little bit," Arquette conceded, though he later admitted that while he’s got a wonderful, honest friendship with Cox, they’re incompatible.

The racy interview was far from the first time Stern got Arquette talking in-depth about the split: Last fall, right after their separation was publicly announced, Arquette told the King of All Media that Cox had grown tired of his sometimes-childish ways.